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 Ultram
for Pain Relief
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Ultram is a non-opioid
analgesic used for pain relief and pain prevention, also commonly
used as arthritis treatment. Tramadol is the generic form
of Ultram.
More about Ultram (Tramadol)
for pain relief… |
| Drug |
Quantity |
Price |
Ship |
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| Ultram
50mg |
30
tabs |
|
|
 |
| Ultram
50mg |
60
tabs |
|
|
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| Ultram
50mg |
90
tabs |
|
|
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| Tramadol 50mg |
30
tabs |
|
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| Tramadol
50mg |
90
tabs |
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Shipping
All orders are currently shipped via FedEx Next Day Air. You can track your
shipment online by clicking on the Order Tracking link on this page.
Service is not provided in Arizona, Arkansas, Florida, Iowa, Missouri, Montana, Nevada, Ohio, Texas or Virginia. Orders approved by the Doctors prior to 2pm Eastern Standard Time Monday through Friday will be received by customers before 3pm the following business day.
Order Process
You will be required to fill out some basic information about your health.
Your medical questionnaire will be reviewed by a U.S. licensed doctor who will
contact you for a phone consultation if necessary, at no additional charge.
If approved, the prescription will be filled by a US licensed pharmacy and
shipped right to your door. Doctor approval may take up to 24 hours.
Refills
You may select an automatic refill option when ordering. Your next prescription
will automatically ship to your home, within five days of expiration of your
current prescription.
More
About Ultram (Tramadol)
What
form does Tramadol (Ultram) come in?
Ultram is the brand name for Tramadol (generic form). Tramadol is
a white, bitter, crystalline, odorless powder. Each Ultram tablet
contains 50mg of Tramadol hydrochloride and is white, film-coated
capsule-shaped tablet. The tablet is engraved with "McNeil"
on one side and "659" on the other.
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How
does Ultram work?
Ultram is a synthetic analgesic compound (unlike codeine and its
derivative medications). Ultram acts on the central nervous system
to control pain. Though its mode of action is not completely understood,
from animal tests, at least two complementary mechanisms are prevalent:
binding of parent compound and its metabolite to opioid receptors
and weak inhibition of reuptake of nor epinephrine and serotonin
by nerves located within the central nervous system.
Ultram-induced analgesia is only partially reversed by the opiate
antagonist naloxone in several animal tests. Ultram demonstrated
ability to inhibit reuptake of nor epinephrine and serotonin in
vitro. These mechanisms may contribute independently to the overall
analgesic profile of Ultram. Analgesic effect in humans begins about
one hour after administration and peaks in approximately 2-3 hours.
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How effective is Ultram for arthritis
treatment?
In clinical studies, Ultram was given to patients in single oral
doses of 50, 75, 100, 150 and 200mg. These patients were experiencing
pain following surgical procedures and oral surgery (extraction
of impacted molars). In single-dose models of pain following oral
surgery, pain relief was achieved in some patients at doses of 50mg
and 75mg. A 100mg Ultram dose provided analgesia superior to codeine
sulfate 60mg, but was not as effective as the combination of aspirin
650mg with codeine phosphate 60mg. In single-dose models of pain
following surgical procedures, 150mg provided analgesia generally
comparable to the combination of acetaminophen 650mg with propoxyphene
napsylate 100mg, with a tendency toward later peak effect.
Ultram pain relief pills have been studied in 3 long-term controlled
trials of 820 patients, with 530 receiving Ultram pain relief treatment.
Patients with a variety of chronic painful conditions were studied
in double-blind trials of 1-3 months. The average daily Ultram dose
was approximately 250mg in divided doses comparable with 5 doses
of acetaminophen 300mg with codeine phosphate 30mg (Tylenol with
Codeine #3) daily, 5 doses of aspirin 325mg with codeine phosphate
30mg daily, or 2-3 doses of acetaminophen 500mg with oxycodone hydrochloride
5mg (Tylox) daily.
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Ultram
dosage
For the treatment of pain:
Ultram 50mg-100mg can be administered as needed for relief every
4-6 hours, not to exceed 400mg daily.
For moderate pain:
Ultram 50mg may be adequate as the initial dose
For severe pain:
Ultram 100mg is usually more effective as the initial dose.
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Dosage
considerations
Patients 65-75 years old: No dose adjustment necessary.
Patients over 75 years old: No more then 300mg/day in divided
doses
Patients with cirrhosis: Recommended dosage is 50mg every
12 hours.
Patients with kidney impairment: The dosing interval of Ultram
should be increased to 12 hours with 200mg maximum daily dose.
Dialysis patients: These patients can receive their regular
dose on the day of dialysis.
Patients receiving chronic carbamazepine: Doses up to 800mg
daily may be required, this is up to twice the recommended dose
of Ultram.
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Ultram
side effects
Ultram was administered to 550 patients during the double-blind
or open-label extension periods in U.S. studies of chronic non-malignant
pain. Of these patients, 375 were 65 years old or older. The table
below reports the cumulative incidence rate of adverse reactions
by 7, 30 and 90 days for the most frequent reactions (5% or more
by 7 days).
Most frequently reported events were in the gastrointestinal system
and central nervous system. Although reactions listed in the table
are felt to be probably related to Ultram administration, the reported
rates also include some events that may have been due to underlying
disease or concomitant medication usage.
Overall incidence rates of adverse experiences in these trials were
similar for Ultram and the active control groups, acetaminophen
300mg with codeine phosphate 30mg, and aspirin 325mg with codeine
phosphate 30mg.
| Cumulative Incidence
of Adverse Reactions for Tramadol HCl In Chronic Trials of
Nonmalignant Pain (N = 427) |
| Symptoms |
Up to 7 Days |
Up to 30 Days |
Up to 90 Days |
| Dizziness/Vertigo |
26% |
31% |
33% |
| Nausea |
24% |
34% |
40% |
| Constipation |
24% |
38% |
46% |
| Headache |
18% |
26% |
32% |
| Somnolence (Sleepiness) |
16% |
23% |
25% |
| Vomiting |
9% |
13% |
17% |
| Pruritus |
8% |
10% |
11% |
| "CNS Stimulation"
(1) |
7% |
11% |
14% |
| Asthenia (Weakness) |
6% |
11% |
12% |
| Sweating |
6% |
7% |
9% |
| Dyspepsia (Acid Indigestion) |
5% |
9% |
13% |
| Dry Mouth |
5% |
9% |
10% |
| Diarrhea |
5% |
6% |
10% |
| (1) "CNS Stimulation"
is a composite of nervousness, anxiety, agitation, tremor,
spasticity, euphoria, emotional lability and hallucinations.
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Drug
abuse and dependence
Ultram has potential to cause psychic and physical dependence of
the morphone-type. The drug has been associated with craving, drug-seeking
behavior and tolerance development. Such cases of abuse and dependence
on Ultram pain relief pills have been reported.
Opioid-dependent patients should not use Ultram since Ultram can
re-initiate physical dependence in patients previously dependent
or chronically using other opioid drugs. In patients with a tendency
to abuse drugs, history of drug dependence or chronic opioid use,
Ultram is not recommended.
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Ultram
and seizures
Seizures have been reported in patients receiving the recommended
dosage of Ultram. Concomitant use of Ultram increases seizure risk
in patients taking any of the following:
• Selective serotonin re-uptake inhibitors (SSRI antidepressants
or anoretics-phentermine)
• Tricyclic antidepressants and other tricyclic compounds (cyclobenzaprine,
promethazine, etc.)
• Opioids
• Neuroleptics
• MAO inhibitors
• Any drugs that reduce seizure threshold
• Epilepsy medication
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Ultram
and drowsiness
Ultram may impair mental or physical abilities needed for performance
of potentially hazardous tasks such as operating machinery or driving.
Ultram should not be taken with alcohol.
Ultram should be used with caution when taking tranquilizers, hypnotics
or other opiate containing analgesics.
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Ultram
and pregnancy
• Ultram should not be used in pregnant women or nursing mothers;
safe use of Ultram during pregnancy is undetermined.
• Chronic use during pregnancy may lead to physical dependence
and post-pregnancy withdrawal symptoms in the newborn child.
• Ultram has been shown to cross the placenta
• The effect of Ultram, if any, on later growth, development,
and functional maturation of the child is unknown.
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Ultram
medication overdose
Serious potential consequences of overdosage are:
• respiratory depression
• seizure
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Additional questions?
Your safety is our utmost concern. If you have additional questions
about Ultram, we suggest you contact your physician
or email us at patient-care@myprivatedrugstore.com.
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Xenical